Research Article
Open Access
Environmental exposure to lead and cadmium in patients with preeclampsia; A case-control study
Alaa M. Ismail ', Safaa M. George *, Asmaa H. Mohamed ?, Ahmed M. Abbas
' Department of Obstetrics and Gynecology, Faculty of Medicine, Assiut
University, Egypt.
Department of Forensic Medicine and Clinical Toxicology, Faculty of Medicine,
Assiut University, Egypt.
Alaa M. Ismail, Safaa M. George, Asmaa H. Mohamed, Ahmed M. Abbas. Environmental exposure to lead and cadmium in patients with preeclampsia; A case-control study. Asian Journal of Pharmacology and Toxicology, 03(12), 2015, 27-33.
Abstract
Objectives:
High blood lead and cadmium levels were associated with adverse
pregnancy outcomes including preeclampsia. The aim of the current
study was to evaluate the relationship between blood lead and
cadmium levels in pregnant females and preeclampsia.
Methods:
A total of 130 pregnant women were enrolled in the study; 80 of them
were suffering from preeclampsia (preeclampsia group) and 50
healthy pregnant women taken as (control group).
Results:
There was significant increase in blood lead level among the
preeclampsia group (p value=0.001) when compared with the control
group. Also, cadmium level was significantly higher in the
preeclampsia group (p value=0.017) when compared with the control
group.
Conclusion:
The results of this study revealed that high blood lead and cadmium
levels were significant risk factors for development of preeclampsia
Keywords
Preeclampsia, environmental toxins, cadmium, lead.