Antidiabetic Activity of Spermadictyonsuaveolens in Streptozotocin Induced Diabetic Rat Model

Anuradha VivekanandPhatak and Kedar SudhirPrabhavalkar


Aim of the study was to study effects of repeated dose administration of extract of roots of Spermadictyonsuaveolens in streptozotocin induced diabetic rats.Effects of extract of Spermadictyonsuaveolens wasstudied in streptozotocin-induced diabetic rats. 1 week after the administration of streptozotocin, diabetic rats received herbal extract orally at dose 500 mg/kg body weight for 28 consecutive days.Administration of streptozotocin resulted in 3-4 fold increase in fasting plasma glucose level. Treatment with herbal extract showed glucose lowering effect from first week. Results show that extract of roots of Spermadictyonsuaveolens possesses antidiabetic activity.